Psych Central


Interconnected brain areas that use split-second timing to interpret new information suffer a communication breakdown in people with schizophrenia, a new study suggests.

The finding hinges on measurements of some brain waves that arise from synchronized activity in large clusters of neurons.

In healthy adults listening to two different tones in a sequence, for example, these aligned brain waves occur about one-tenth of a second after a person first recognizes the tones’ difference, say neuroscientist Leanne M. Williams of Westmead (Australia) Hospital and her colleagues. The synchronized electrical outbursts appear most prominently in the frontal brain, a region regarded as a key part of a network that interprets novel perceptions against a background of prior knowledge.

In contrast, people diagnosed with their first bout of schizophrenia display a decline in neural synchrony, especially in the frontal brain, in the fraction of a second after discerning a particular tone, Williams’ team reports in the March American Journal of Psychiatry. Individuals with schizophrenia exhibit unusually low levels of synchronized neural firing to begin with, the researchers note.

If confirmed in further work, these findings raise the likelihood that “a breakdown in the synchrony of distributed neural networks is a marker for the onset of schizophrenia,” the researchers conclude.

 


Comments


View Comments / Leave a Comment

This post currently has 0 comments.
You can read the comments or leave your own thoughts.


    Last reviewed: By John M. Grohol, Psy.D. on 25 Jan 2006
    Published on PsychCentral.com. All rights reserved.

APA Reference
Bolognese, P. (2006). Schizophrenia syncs fast: disconnected brain may lie at heart of disorder. Psych Central. Retrieved on April 18, 2014, from http://psychcentral.com/blog/archives/2006/01/25/schizophrenia-syncs-fast-disconnected-brain-may-lie-at-heart-of-disorder/

 

Recent Comments
  • Elizabeth: This is one of my favorite of your recent posts. I am the same as you were when you said: “Like most...
  • Elizabeth: I read this post a few weeks ago and found it really interesting and I want to read her book. My father is...
  • Hello: When you say people can rise above this using other means…what are these other ways? IMHO bullying works...
  • Maureen: Hi I dont know if” i am in a abusive relationhship even though i know i should as i was in one before...
  • Fritters: I have the same “what now” question.
Subscribe to Our Weekly Newsletter


Find a Therapist
Enter ZIP or postal code



Users Online: 6444
Join Us Now!