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World of Psychology

Switching depression treatment can help

Depressed individuals who fail to respond to initial treatment with an antidepressant or psychotherapy may do better if they are switched to the alternative treatment, new study findings suggest.

“Surprisingly few studies have evaluated the role of medication following nonresponse to psychotherapy,” the authors of the study say and “none has evaluated the efficacy of psychotherapy following nonresponse to medication.”

Dr. Alan F. Schatzberg, at Stanford University in California, and associates followed 140 patients who failed initial treatment with the antidepressant Serzone (nefazodone) or cognitive behavioral psychotherapy. Thirty patients dropped out of the study. Patients were crossed over from Serzone to psychotherapy or from psychotherapy to Serzone.


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2 Comments to
“Switching depression treatment can help”

Was there any mention in the article as to the reasons why they lost 30 patients? Also, what were “the alternative treatment[s]” the authors suggested using?

Thanks, Matthew

My health care professional switched me to Lamictal to treat dysthimetic reaction (mild recurrent depression). It seems to very effective but I have to watch my dosage. Large doses can cause me to have a balance problem and results in falls.

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    Last reviewed: By John M. Grohol, Psy.D. on 9 May 2005

 


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